URO-ONCOLOGY

Bladder cancer

Treatment depends on the depth and grade of the tumour, earlier treatments and the broader goals of care.

AT A GLANCE
  • Tumour depth changes the pathway
  • Bladder preservation may be possible
  • Reconstruction needs preparation

Clarifying the stage

Cystoscopy and transurethral resection of bladder tumour (TURBT) help establish the diagnosis. The pathology report describes grade and whether the tumour has reached the bladder muscle. Repeat resection or further imaging may sometimes be needed.

Blood in the urine should be assessed even if it is painless or occurs only once. It can have causes other than cancer, but should not be assumed to be harmless.

Different treatment pathways

For non-muscle-invasive disease, care may involve TURBT, medicines delivered into the bladder and continued cystoscopic monitoring. High-risk or treatment-resistant disease may lead to a discussion of bladder removal.

Muscle-invasive cancer may require radical cystectomy with consideration of systemic treatment. A bladder-preserving combination of resection, chemotherapy and radiotherapy is suitable for some patients after careful assessment.

Discussing cystectomy and reconstruction

Dr. Sachin’s practice includes robotic cystectomy and urinary reconstruction. The consultation can explore an ileal conduit, a neobladder where appropriate, and whether organ or nerve preservation is oncologically reasonable.

These decisions require discussion of kidney function, the cancer’s location, continence, sexual health and the ability to manage the proposed reconstruction.

Preparing for a treatment decision

  • Bring previous TURBT operation notes, pathology reports and scans.
  • Record any BCG or other bladder treatments and their dates.
  • Ask whether a repeat pathology or multidisciplinary review would help.
  • Discuss stoma support, continence and recovery before surgery.

Common questions

Does bladder cancer always mean bladder removal?

No. Treatment varies substantially by stage, risk and response to earlier treatment.

Can a neobladder be offered to everyone?

No. Cancer-related factors, kidney function and the practical demands of emptying and continence have to be assessed first.

References & further reading
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